Regulation of tapetum-specificA9promoter by transcription factors AtMYB80, AtMYB1 and AtMYB4 inArabidopsis thalianaandNicotiana tabacum

Down Regulation of DHFR Promoter Activity by PML Transcription Repressor

Regulation of endochondral ossification by transcription factors.

Endochondral ossification is very unique and complex biological event which is associated with skeletal development and tissue partnering. Genetic studies and gene-targeting approaches identified several transcription factors that play important roles in endochondral ossification. These transcription factors sequentially and harmoniously regulate each step of endochondral ossification, and cons...

Regulation of transcription factors by sumoylation

Transcription factors (TFs) are among the most frequently detected targets of sumoylation, and effects of the modification have been studied for about 200 individual TFs to date. TF sumoylation is most often associated with reduced target gene expression, which can be mediated by enhanced interactions with corepressors or by interference with protein modifications that promote transcription. Ho...

Regulation of angiogenesis by ETS transcription factors.

Transcription factors of the ETS family are important regulators of endothelial gene expression. Here, we review the evidence that ETS factors regulate angiogenesis and briefly discuss the target genes and pathways involved. Finally, we discuss novel evidence that shows how these transcription factors act in a combinatorial fashion with others, through composite sites that may be crucial in det...

Combinatorial gene regulation by eukaryotic transcription factors.

Recent structure determinations of high order complexes of eukaryotic transcription factors bound to DNA have revealed that residues from their DNA-binding domains are involved in protein-protein interactions between distinct factors. Protein-protein interactions between transactivation domains and coactivators have also been characterized in a number of recently determined structures. These st...